AGO2 and viral infectious disease: Two non-exclusive explanations may account for this: (1) the DCV and FHV viral suppressors of RNAi (8) trigger the degradation of Dcr-2 and Ago-2 in a similar fashion to that observed for Cricket Paralysis Virus (CrPV) (49); (2) the later activation of other unknown immunological processes to fight viral infection inhibits Dcr-2 and Ago-2 from being produced.