EGFR and neoplasm: Yu et al. transduced human NK cell lines NK-92 and NKL and primary NK cells with a lentivirus containing anti-EGFR CAR to evaluate the anti-GB efficacy; they found that intracranial administration of anti-EGFR CAR NK-92 cells resulted in efficient suppression of tumor growth and significantly prolonged the survival of tumor-bearing mice (62).