Out of 87 investigated cytokines and chemokines, CXCL-10, CXCL-11, CXCL-13, CCL-1, CCL-2, CCL-3, CCL-22, IL-16, and BAFF CSF concentrations significantly differed between RRMS patients and ONIND (Figure 1 and Supplementary Material 2). This evidence concerns the gene CCL2 and relapsing-remitting multiple sclerosis.