PARP1 and glioblastoma: 18F-PARPi is an olaparib-based PET imaging agent that exhibits high specificity for PARP1 in mouse models of orthotopic glioblastoma, diffuse intrinsic pontine glioma, and small-cell lung cancer (Carney et al., 2016; Kossatz et al., 2017; Carney et al., 2018) (Figures 2C, D).