CRP and atherosclerosis: A possible reason for this is that the commonly used CHP, such as Gui-Zhi-Shao-Yao-Zhi-Mu-Tang, alleviate systemic inflammation by lowering the CRP, and erythrocyte sedimentation rate (ESR), which may decrease the progression of atherosclerosis, the main pathologic process of IS (Daily et al., 2017).