Zhang et al. (2015a) even indicated that the CCR5-Δ32 increased the risk of atherosclerotic disease in Asian population (Zhang et al., 2015a). Moreover, previous studies have reported that a CCR5 gene promoter region mutation (CCR5-59029 G/A) was an independent risk factor for CVD (Simeoni et al., 2004; Vogiatzi et al., 2009). The CCR5 59029A-positive genotype was correlated with an increased risk of acute coronary syndrome (Ting et al., 2015). Here, CCR5 is linked to acute coronary syndrome.