Changes in the expression of α2A-adrenergic, TRPV1, and NMDA NR2B receptors in the LPS-induced SH-SY5Y neuroblastoma cells were analyzed 24 h after the administration of 8 μg/ml zerumbone, 16 μg/ml amitriptyline, and vehicle. This evidence concerns the gene IGKV2D-29 and neuroblastoma.