ALK and anaplastic large cell lymphoma: ALK+ Karpas 299 and SU-DHL-1 ALCL cell lines have been instrumental in the cloning of the genes involved in t(2;5) translocation, have served as references for studies on biopsy material29,30, have been used to elucidate the molecular mechanisms of these specific malignancies27,31–34 and are ultimately useful for drug development and preclinical testing31,35–37.