PAI-1 concentration in the CSF of controls was 0.63 ng/mL (± 0.18 IQR) while in the CSF of MS patients the concentration was 0.75 ng/mL (± 0.13 IQR), but this difference was not significant (t = 1.82, p = 0.079) (Fig. 3b). The gene discussed is SERPINE1; the disease is myeloid sarcoma.