XRCC1 and breast cancer: Moreover, a nominal association of the XRCC1-rs25487 polymorphism was found with family history of BC, with G/A genotype associated in both the codominant and overdominant models (OR: 2.19; 95% CI: 1.04–4.62, p = 0.0393 and OR: 2.16; 95% CI: 1.06–4.41, p = 0.0337) respectively, no other significant association was found with the other clinicopathological features (Table 6).