Thus, predictive phosphorylation markers for the treatment of AML with FLT3 inhibitor quizartinib, the description of the phosphotyrosine-proteome, tyrosine-kinome and tyrosine-phosphatome in AML, and the identification of sensitivity determinants of AML cells to kinase inhibitors have been recently described [27,28,29]. The gene discussed is FLT3; the disease is acute myeloid leukemia.