Venn diagram analysis showed that AD and VaD shared 21 transcription factors (IRF1, ZFX, REST, CTCF, PPARG, CREB1, YY1, ARNT, STAT1, GATA1, GATA2, GATA3, SREBF1, SREBF2, RELA, FOXA2, MYB, E2F4, JUN, SRF, ESR1) whereas AD and FTD shared one transcription factor, EGR1. Here, SREBF1 is linked to frontotemporal dementia.