In the context of non-small cell lung cancer, Yang and colleagues showed that TGF-β- induced miR-145 reduced the expression of miR-20a by targeting c-myc, resulting in enhanced expression of its target transforming growth factor beta receptor II TGFBRII and sensitizing cells to TGF-β treatment [88]. The gene discussed is TGFB1; the disease is non-small cell lung carcinoma.