In thyroid cancer, it has been found that the UbcH10 protein is abundantly expressed in many thyroid carcinoma-derived cell lines, such as TPC-1, WRO, NPA, ARO, FRO, NIM 1, B-CPAP, FB-1, Kat-4 and Kat-18, whereas the protein levels are barely detectable in normal thyroid cells [30]. The gene discussed is CYP19A1; the disease is thyroid gland carcinoma.