To further investigate the dependence of lung cancer harboring the NRASQ61 mutation on MEK signaling, we tested three NRAS mutant non‐small‐cell lung cancer (NSCLC) lines (H1299:NRASQ61K, large‐cell carcinoma; H2087:NRASQ61K, adenocarcinoma; H2347:NRASQ61R, adenocarcinoma) for sensitivity to MEK inhibitors. Here, NRAS is linked to lung cancer.