It is reported to be in strong linkagedisequilibrium with cell cycle proliferatory genes such as cyclin dependantkinase inhibitors 2A and 2B (CDKN2A and CDKN2B) (Cunnington et al., 2010).CDKN2A is basically a tumor suppressor gene and encodes twoproteins viz. p14ARF and p16. This evidence concerns the gene CDKN2A and neoplasm.