IPA analysis of the differentially expressed genes showed significant enrichment for pathways involved in glycolysis I, gluconeogenesis I, NRF2 (nuclear factor, erythroid derived 2, like 2)-mediated oxidative stress response, glutathione-mediated detoxification, SPINK1 general cancer pathway, and MIF regulation of innate immunity (S4B Fig). Here, SPINK1 is linked to cancer.