VAV1 and diabetes mellitus: Rahaman et al. and Chen et al. found that the degree of Vav1 phosphorylation was increased in atherosclerotic plaques, while knocking out Vav1 reduced plaque area [8, 9]; in vitro experiments showed that the loss of the Vav1 gene recovered the migratory ability of oxLDL-induced foam cells [10], but whether the migration of foam cells is affected by Vav1 gene expression and phosphorylation in diabetes is not clear.