Amount of fluid per body weight significantly lower in overweight and obese patients Day 1 through Day 4; p<0.0001   Days alive and free of renal replacement therapy (obese 25, overweight 24, BMI<25 kg/m2 24 days; p=0.93)   Norepinephrine: Obese 0.14, IQR 0.09-0.25 Overweight 0.21, IQR 0.12-0.34 BMI <25 kg/m2 0.26, IQR 0.15-0.44 μg/kg/minute; p< 0.0001   IL-6 significantly lower in obese and overweight compared to <25kg/m2 in early phase of septic shock; p=0.046. This evidence concerns the gene IL6 and Shock.