PTGS1 and cardiovascular disorder: Luteolin acting on PTGS1, PTGS2, AR, and APP could depress hypertensive aorta remodeling in spontaneous hypertensive rats, relax porcine coronary and aortic arteries, and improve cardiac function after myocardium ischemia/reperfusion injury [41, 42], which is vital to the treatment of cardiovascular diseases contained by HH, JG, XF, and ZQ.