Additionally, Flow cytometry analysis showed increased apoptosis in both cell types after transfection by Ad-sta-SFv (19.84% in HeLa cells, 23.88% in SiHa cells, respectively, as well as the increasing activity of caspase-3 in HeLa/Ad-sta-SFv and SiHa/Ad-sta-SFv cells has been indicated that blocking AEG-1 could induce tumor cell apoptosis. This evidence concerns the gene CASP3 and neoplasm.