Currently, no recognized biochemical diagnostic indicators are available for NAFLD, AST, ALT and ALP can only be used only as the auxiliary diagnostic indicators for NAFLD or for differential diagnosis with NASH and fibrosis.3, 22, 23 Abnormal blood lipids are characterized by an increase in TG and LDL‐C, and a decrease in HDL‐C levels.3, 24, 25 GLU is also an important biochemical factor in NAFLD and an important substrate in the synthesis of lipids.26, 27 In the present study, the serum levels of TG, TC, HDL‐C and GLU in the CSP group were significantly lower than those in the HFD group. This evidence concerns the gene GPT and metabolic dysfunction-associated steatohepatitis.