Quercetin, kaempferol, naringenin, isorhamnetin and nobiletin were screened as the top 5 compounds derived from six herbs: Radix Bupleuri, Citrus Reticulata, Paeoniae Radix Alba, Aurantii Fructus, Cyperi Rhizoma and Radix Glycyrrhizae, with each compound derived from at least two of these herbs, suggesting that the top 5 compounds may function through PPARγ, PPARα and PPARδ to affect NAFLD (Figure 5). The gene discussed is PPARD; the disease is metabolic dysfunction-associated steatotic liver disease.