Also, correlation analyses between Nurr1 gene expression of ALS patients and age at the time of sampling (Pearson correlation coefficient r=−0.09, P=0.55) and age at disease onset (Pearson correlation coefficient r=−0.16, P=0.31) (Fig. S1A) did not highlight significant results. The gene discussed is NR4A2; the disease is amyotrophic lateral sclerosis.