Overall, differential expression analysis between HV and septic shock patients confirmed that septic shock is associated with an early modulation of thousands of HERV/MaLR loci, which is in agreement with (1) in vitro LTR retrotransposons being tightly regulated to endotoxin-induced stress [13] and (2) in vivo preliminary observations in critically ill patients [12]. The gene discussed is LINC02154; the disease is septic shock.