EDARADD and neoplasm: EDARADD mRNA levels were significantly higher in CAFs from grade group ≥ 4 tumours compared to all other groups of fibroblasts (BPFs, GG ≤ 3 NPFs, GG ≥ 4 NPFs and GG ≤ 3 CAFs), as measured using qPCR (Fig. 4a).