The intergenic non-protein coding RNA 00511 (LINC00511) participates in a subnetwork with HOTAIR (HOX transcript antisense RNA), which is linked to the methyltransferase EZH2 and causes impaired cell proliferation and inhibition of apoptosis in estrogen receptor (ER) negative BC cells [154]; indeed, LINC00511 promotes metastasis dissemination by silencing NLK [155]. This evidence concerns the gene ESR1 and breast cancer.