HULC and osteosarcoma: It has been demonstrated that miR-372-3p regulates cell growth and metastasis by targeting FGF9 in lung squamous cell carcinoma.(Wang et al. 2017b) Another report revealed that miR-372-3p inhibited the growth and metastasis of osteosarcoma cells by targeting FXYD6.(Xu et al. 2018) HULC could act as an endogenous sponge antagomir to downregulate miR-372 expression in hepatic cell carcinoma.(Wang et al. 2010) However, whether HULC acts as a ceRNA to reduce miR-372-3p expression in OS needs further exploration.