STAT3 and T-cell large granular lymphocyte leukemia: Activating mutations of JAK1-3 and STAT3-5 have also been found in a subset of NK/T-cell lymphomas, non-hepatosplenic gamma-delta T-cell lymphoma, large granular lymphocytic leukemia and T-cell prolymphocytic leukemia [10,17,18,19,20,21,22].