TF and autoimmune polyendocrinopathy: In line with these studies, our study demonstrated that specific autoantibodies from APS and SLE patients (aPL-IgG and anti-ds-DNA-IgG, respectively) downregulated in ECs all the miRNAs evaluated and altered the expression of several markers of endothelial dysfunction, such as TF, VCAM-1 and eNOS.