TNF and rheumatoid arthritis: In a cohort of 90 RA patients the expression levels of miR-16-5p, miR-23-3p, miR125b-5p, miR-126-3p, miRN-146a-5p, miR-223-3p were up-regulated in the serum of these patients after 6 months of TNFα/DMARDs combination therapy.