On the other hand, we have previously demonstrated that astragaloside IV (ASV), the active substances of traditional Chinese medicinal plant astragalus membranaceus, inhibited TGF‐β1‐mediated EMT.15 Therefore, we also explored the regulation of ASV on MTA1 expression, to provide a potentially effective agent that targeting MTA1 in IPF. This evidence concerns the gene TGFB1 and idiopathic pulmonary fibrosis.