In the Québec Family Study, a variant of the melanocortin‐4 receptor (MC4R) gene was found to be associated with a combined measure of self‐reported sedentary time and physical inactivity28 and in the Framingham Heart study an association of the fat mass and obesity‐associated (FTO) gene with sitting time was reported.29 The gene discussed is MC4R; the disease is obesity due to melanocortin 4 receptor deficiency.