If positive, aPL should be repeated after 3 months to diagnose definite APS.30 A systematic review showed that aPL were detected in 17.2% (2–56%) of patients with stroke and 11.7% (2–45%) of transient ischemic attack (TIA); conversely, the presence of aPL increases the risk for stroke approximately 5-fold.31 This evidence concerns the gene FASLG and Stroke.