CD4 and synovial sarcoma: In CD4 T lymphocytes, -let-7d-3p, -miR-155-5p, miR-22-3p, -miR-30c-5p, -miR-146a-5p, -miR-378a-3p and –miR-28-5p were significantly differentially expressed in both the discovery and the replication cohort.14 Johansson et al. suggested in all, that reduced levels of miR-31-5p in T cells of SS patients support auto-immune T-cell responses during chronic type I IFN exposure.15 Furthermore, in a cohort of 28 pSS patients, Wang et al. demonstrated reduced expression levels of miR-181 and -16 in labial salivary gland tissues of SS patients.