Its prevalence in adults in Europe ranges from 34% to 67%.7 Vitamin D deficiency is more prevalent among SLE patients, possibly due to sun avoidance and renal impairment in lupus nephritis.8 The expression of vitamin D receptors by a variety of cells belonging to the innate and adaptive immune systems (including macrophages, dendritic cells, T cells and B cells) has created interest with regards to the role of vitamin D in the pathogenesis of SLE.9 It is still unknown whether vitamin D deficiency alters the course and prognosis of SLE. Here, VDR is linked to vitamin D deficiency.