Others have shown that in adriamycin-induced glomerulonephritis, a model of chronic proteinuric renal injury, treatment of animals with IL-33 improved the course of the disease via an ILC2-mediated induction of protective type 2 response; the treatment also increased IL-5 which promoted accumulation of eosinophils in the kidney and ameliorated glomerulonephritis [23]. This evidence concerns the gene IL5 and glomerulonephritis.