Hoang et al. [27] reported that the prevalence in the male was 2.33 times higher than that in females in Vietnam, which supports our finding that more male clonorchiasis patients identified in southern China were susceptible to biliary or pancreatic disorders, including jaundice and elevated hepatic biochemical markers of TBil, DBil, ALT, AST, ALP, and GGT. This evidence concerns the gene GPT and clonorchiasis.