Moreover, EMT is involved in all types of signaling pathways (e.g., NF-kB, EGFR–ERK, BMP, Wnt/β-catenin, Akt/GSK-3b/Snail, EGF/EGFR, p53/TIGAR and SCO2 pathways), which are regulated by the zinc-finger family of transcription factors, including Snail, Slug, and Twist, which contribute to tumor metastasis by promoting EMT in cervical carcinoma (Qureshi et al., 2015). This evidence concerns the gene TWIST1 and neoplasm.