PIMREG and neoplasm: The introduction of FAM64A siRNA into MG-63 and U-2 OS cells resulted in impeded tumor cell proliferation (Figures 3(c) and 3(d); P < 0.05), migration (Figures 3(e) and 3(f); P < 0.05), and invasion (Figures 3(g) and 3(h); P < 0.05), compared with the Scramble group.