The mRNA expression level of 10 HCSC markers was up-regulated in HCC in at least one database, including CD90, EpCAM, CD133, CD24, CD34, SOX9, ALDH1A1, ALDH3A1, CK19, and SOX12 (Figures 1A–C). This evidence concerns the gene ALDH1A1 and hepatocellular carcinoma.