The mRNA expression level of 10 HCSC markers was up-regulated in HCC in at least one database, including CD90, EpCAM, CD133, CD24, CD34, SOX9, ALDH1A1, ALDH3A1, CK19, and SOX12 (Figures 1A–C). The gene discussed is SOX9; the disease is hepatocellular carcinoma.