To better understand the immune influence of the 9 HCSC markers (CD90, EpCAM, CD133, CD24, SOX9 CD44, CK19, CD47, and SOX12) expression in HCC, 4710 positively related genes with similar expression pattern with the nine HCSC markers were detected in HCC dataset of TCGA by GEPIA. The gene discussed is PROM1; the disease is hepatocellular carcinoma.