Essentially, CALM1 and CALM2 mRNA levels were significantly reduced in resting HNSCC T cells as compared to resting HD T cells, whereas CALM1, CALM2, and CALM3 mRNA levels were significantly lower in activated HNSCC T cells as compared to their activated healthy counterparts (Figures 1C, D). The gene discussed is CALM3; the disease is head and neck squamous cell carcinoma.