GOT2 and obesity due to melanocortin 4 receptor deficiency: Fatty acid-binding proteins (FABPs) are a kind of lipid chaperone protein that can regulate fatty acid transport, signal transduction, and nuclear transcription (Gan et al., 2015), which is closely related to obesity, type-2 diabetes, cardiovascular disease, tumor, fatty liver, and other diseases (Senolt et al., 2010; Kawaguchi et al., 2016; Thompson et al., 2018).