A correlated variant near GDF7 (rs2289081–C, r2 = 0.85) has been associated with decreased pulse pressure58 and rs7255–T (r2 = 0.62 to rs9306894) has been associated with increased risk of Barrett’s oesophagus and esophageal adenocarcinoma combined (BE and EA) (Supplementary Data 10), which we replicate (Supplementary Data 9) but co-localization analysis only supports a single signal origin for BE and AE combined (Supplementary Data 12). The gene discussed is GDF7; the disease is acrodermatitis enteropathica.