LOXL1 and Inguinal hernia: We found variants at nine loci to associate with POP; five of which associate at genome-wide significance with POP, three that were previously associated with height (P < 1.4 × 10−5) at TXNDC5 (6p24.3), SLC12A2 (5q23.3) and LOXL1 (15q24.1) (Supplementary Data 19) and one at WT1 that associates with inguinal hernia (11p13) (Supplementary Data 18).