The POP variants in and near to EFEMP1 did not associate with traits likely to cause lordokyphosis (any fracture and osteoporosis in the ICE-UKB data, and BMD (hip and spine measures)), BMI (both sexes and females only) or lifespan (females) in the Icelandic data (Supplementary Data 27). The gene discussed is EFEMP1; the disease is osteoporosis.