Multivariate logistic regression was employed to estimate the independent relationshipbetween variables with significant differences (p < 0.1) in Tables 1 and 2 (hyperlipidaemia, HB, EF, NT-proBNP, NGAL, H-FABP, Cys C, KIM-1 and miR-21) and thepresence of CRS. The gene discussed is NPPB; the disease is congenital rubella syndrome.