Further research identified seven ALS-related RNA-binding proteins (RBPs), FUS, TAF15, EWSR1, HNRNPA1, HNRNPA2B1, Matrin-3, and TIA1, that are characteristically deposited in the affected regions of the ALS/FTD brain3. The gene discussed is HNRNPA2B1; the disease is amyotrophic lateral sclerosis.