DCC and major depressive disorder: Notably, we found another SNP rs1367635 in DCC, which was genome-wide significantly associated with depression in Europeans (Pdepression = 4.35 × 10−9, OR = 1.026 for C-allele in 170,756 cases and 329,443 controls, Fig. 2), was also highly associated with this illness in Han Chinese (Pdepression = 1.21 × 10−5, OR = 1.173 for C-allele in 5303 cases and 5337 controls, Fig. 2).