PML and infection: In the absence of E2A SUMOylation, there are fewer E2A/PML (Fig. 3C and D and Fig. 8, bottom) and E2A/Sp100A (Fig. 7D to G and Fig. 8, bottom) interactions and increases in Sp100A levels are lower than in wt infection (Fig. 7D and F and Fig. 8, bottom).