INS and familial dilated cardiomyopathy: To evaluate the effect of MSCs on DCM rats, serological parameters including FBG, INS, TC, and TG, ratio of heart weight to body weight (HW/BW), and echocardiography indicators including LVIDD, LVIDS, LVEF, FS, and E’/A’ were performed after 4 MSCs infusions to reflect glucose and lipid metabolism, cardiac structure and function (Fig. 1a).