Subsequently, we divided A2058 and A375 cells into 5 groups (control, si-NC, si-circ-FOXM1, si-circ-FOXM1 + anti-miR-NC, and si-circ-FOXM1 + anti-miR-143-3p) to explore whether circ-FOXM1 could alter melanoma cell progression via targeting miR-143-3p. This evidence concerns the gene FOXM1 and melanoma.