Finally, general CCA transcript biomarkers (compared to PSC, UC and healthy individuals combined as one unique control group) were also identified and RFFL, zinc finger protein 266 (ZNF266) and OR4F3 constituted the mRNA transcripts with the highest AUC values (1.00, 0.976, and 0.960, respectively) while miR-551B, PMS2L4, and LOC643955 were the ncRNAs presenting the highest diagnostic capacity, displaying AUC values of 0.909, 0.880, and 0.873, respectively (Figure 3C). This evidence concerns the gene OR4F3 and cholangiocarcinoma.