A small molecule Magmas inhibitor, BT#9 (compound 9) [121], decreased proliferation in human GBM cell lines (D-54 MG, U-251 MG), murine embryonal stem cell lines (1123 Mes, 83 Mes) and a human glioblastoma stem cell line (HuPuP01). This evidence concerns the gene PAM16 and glioblastoma.